receptor-mediated endocytosis
Receptor-mediated endocytosis creates receptosomes. Cells invaginate proteins and other types of ligands that have attached to specific receptors on the plasma membrane.
1. First, the protein or ligand binds to a specific receptor, forming a coated pit ("coated pit endocytosis"). The coated pit is a specialized membranous region coated with clathrin, which provides stability and aids the transport process.
2. Next, the coated pit next forms a coated vesicle and, shedding its clathrin coat, joins with other coated pits to form a receptosome.
• A • adhesion • C • cell membranes • cellular adhesion molecules • cellular signal transduction • centrioles • chemotaxis • chloroplast • cilia & flagella • communication • concentration gradients • cytokine receptors • cytoplasm • cytoskeleton • E • energy transducers • endoplasmic reticulum • endosomes • exosome • F • flagella & cilia • G • Golgi apparatus • GPCRs • H • hormones • I • ion channels • L • lysosome • M • meiosis • microtubules • mitosis • mitochondrion • N • Nitric Oxide • neurotransmission • neuronal interconnections • nuclear membrane • nuclear pore • P • pinocytosis • proteasome • protein degradation • pumps • R • receptor proteins • receptor-mediated endocytosis • S • second messengers • signaling gradients • signal transduction • spindle • structure • T • transport • two-component systems • U • ubiquitin • V • vacuole • vesicle •
1. First, the protein or ligand binds to a specific receptor, forming a coated pit ("coated pit endocytosis"). The coated pit is a specialized membranous region coated with clathrin, which provides stability and aids the transport process.
2. Next, the coated pit next forms a coated vesicle and, shedding its clathrin coat, joins with other coated pits to form a receptosome.
• A • adhesion • C • cell membranes • cellular adhesion molecules • cellular signal transduction • centrioles • chemotaxis • chloroplast • cilia & flagella • communication • concentration gradients • cytokine receptors • cytoplasm • cytoskeleton • E • energy transducers • endoplasmic reticulum • endosomes • exosome • F • flagella & cilia • G • Golgi apparatus • GPCRs • H • hormones • I • ion channels • L • lysosome • M • meiosis • microtubules • mitosis • mitochondrion • N • Nitric Oxide • neurotransmission • neuronal interconnections • nuclear membrane • nuclear pore • P • pinocytosis • proteasome • protein degradation • pumps • R • receptor proteins • receptor-mediated endocytosis • S • second messengers • signaling gradients • signal transduction • spindle • structure • T • transport • two-component systems • U • ubiquitin • V • vacuole • vesicle •